NanoBrook Series

The NanoBrook Series particle/molecule size and zeta potential analyzers incorporate all you need for fast, routine, sub-micron measurements of size and zeta potential. The instrument incorporates the principles of Dynamic Light Scattering (DLS) for particle sizing and distribution and Doppler Velocimetry (Electrophoretic Light Scattering, or ELS) for zeta potential measurement. The instrument also includes Phase Analysis Light Scattering (PALS) measurements for samples with low mobilities.

Measurements of colloids are traditionally made using a 90° scattering angle. For smaller nanoparticles, proteins including IgG, mAbs, and peptides, these < 50 nm samples can be measured using the backscattering angle (173°). Finally, the 15° detection angle can be selected for added sensitivity with aggregation measurements. Zeta potential measurements are always performed using the 15° detection angle to minimize diffusion broadening.

With the NanoBrook Omni, measure samples in nearly every possible suspension environment from high salts such as PBS and sea water to organic solvents and aqueous solutions. Particle and protein sizing, with the highest sensitivity, utilize three measurement angles for truly unbiased measurement results.

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